Cell-to-cell communication
Study EV signatures from a selected cell type to support cell-resolved communication mapping and targeted biomarker discovery.
THE GENEFRONT APPROACH
From a mixed EV population
to a more focused question.
Each capture plate targets one selected cell type. Cell-specific EV enrichment supports research into cell-to-cell communication mapping and targeted biomarker discovery.
WHY CELL-SPECIFIC CAPTURE?
The source matters
to the signal.
Biofluids contain extracellular vesicles released by many cell populations. Studying an enriched population can help researchers frame more specific biological questions.
EVHook uses a proprietary protein and molecular affinity mix in a pre-coated 96-well plate format. Product selection starts with the target cell type and a compatible EV preparation.
THE WORKFLOW
A considered path from sample to analysis.
Schematic workflow. Follow the relevant product protocol and confirm compatibility with GeneFront.
01
Prepare an EV sample
Start with a compatible total-EV preparation from your biofluid sample.
02
Capture & wash
Use the selected EVHook plate and product-specific protocol.
03
PROTEINRNADNA
Investigate the cargo
Plan downstream protein and nucleic-acid research with an appropriately characterized population.
BUILT AROUND THE RESEARCH QUESTION
Specificity needs evidence.
Capture alone is not a clinical diagnosis or a substitute for tissue biopsy. Discuss the evidence needed for your target population and application.
01
EV identity
Characterization and marker evidence relevant to the isolated population.
02
Capture specificity
Target relevance, cross-reactivity, recovery, and reproducibility.
03
Application fit
Compatibility with your research design and downstream analysis.
WHY STUDY A CELL-SPECIFIC EV POPULATION?
From a mixed sample to a more resolved question.
Cell-specific enrichment can help researchers investigate a chosen population within a heterogeneous EV sample.
Molecular profiling
Plan protein, lipid, metabolite, DNA, or RNA investigations around a compatible downstream workflow.
Longitudinal research
Explore potential biomarkers of disease progression, prognosis, treatment response, and recurrence through serial sampling.
Stratification & response
Investigate molecular signatures for patient-stratification and pharmacodynamic research, and future companion-diagnostic development.
These are research directions, not validated diagnostic uses of every EVHook product. Confirm target-marker specificity, EV identity, recovery, cross-reactivity, reproducibility, and application-specific evidence.
START A CONVERSATION
Let’s move your next question forward.
Connect with GeneFront about products, technical information, research collaborations, or investment and partnership discussions.